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Medication that inhibit CYP2D6 exercise, which include paroxetine and quinidine, could result in lowered clearance of oxycodone which may lead to an increase in oxycodone plasma concentrations. Concurrent administration of quinidine resulted in a rise in oxycodone Cmax by 11%, AUC by 13%, and t½ elim.These strengths could bring about overdose (eve